Results

COVID19-hg GWAS meta-analyses round 2

Release Date

May 15, 2020

Study Abbreviations
Full NameAbbreviation
BioMeBioMe_RGN
FinnGenFinnGen
Genes & HealthGNH
Helix Exome+ COVID-19 PhenotypesHelix
LifeLines Global Screening ArrayLifelinesCyto
LifeLines CytoSNPLifelinesGsa
Netherlands Twin RegisterNTR
Partners Healthcare BiobankPHBB
UK BiobankUKBB
Release Notes

Meta-analysis was done with inverse variance weighting. Positions are on GRCh37. An AF filter of 0.0001 and an INFO filter of 0.6 was applied to each study prior to meta-analysis.

Data Columns
Column NameDescription
#CHRchromosome
POSchromosome position in build 37
REFnon-effect allele
ALTeffect allele (beta is for this allele)
SNP#CHR:POS:REF:ALT
{STUDY}_AF_Allele2allele frequency in {STUDY}
all_meta_Nnumber of studies that had the variant after AF and INFO filtering and as such were used for the meta
all_inv_var_meta_betaeffect size on log(OR) scale
all_inv_var_meta_sebetastandard error of effect size
all_inv_var_meta_pp-value
all_inv_var_het_pp-value from Cochran's Q heterogeneity test

An interactive data browser will be available soon.

20200508-results-ANA2_inv_var_meta

Phenotype

ANA2, Hospitalized vs. non-hospitalized

Population

All

Total Cases

716

Total Controls

616

Contributing Studies
Namen_casesn_controls
FinnGen_FIN30179
GNH_SAS3413
LifelinesGsa_EUR6183
PHBB_EUR1757
UKBB_EUR629184
Downloads
20200508-results-ANA5_ALL_inv_var_meta

Phenotype

ANA5, susceptibility (affected vs. population)

Population

All

Total Cases

1678

Total Controls

674635

Contributing Studies
Namen_casesn_controls
BioMe_RGN_EUR2010169
FinnGen_FIN209203431
GNH_SAS6427351
LifelinesCyto_EUR625750
LifelinesGsa_EUR18915975
NTR_CEU1633160
PHBB_AFR342169
PHBB_EUR7428950
UKBB_AFR516585
UKBB_EUR812371095
Downloads
20200508-results-ANA7_inv_var_meta

Phenotype

ANA7, COVID-19 predicted by flu-like symptoms

Population

European

Total Cases

1294

Total Controls

26969

Contributing Studies
Namen_casesn_controls
LifelinesGsa_EUR44315406
LifelinesCyto_EUR1945451
Helix_EUR6576112
Downloads